Tag Archives: Therapy

Bacterial therapy in a dish

Engineering bacteria to intelligently sense and respond to disease states, from infections to cancer, has become a promising focus of synthetic biology. Rapid advances in genetic engineering tools have enabled researchers to “program” cells to perform various sophisticated tasks. For example, a network of genes can be wired together to form a genetic circuit in… Read More »

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Three years after undergoing gene therapy, his ‘last shot’ hit the target

Brenden was the first patient enrolled in what became a nine-patient, four-center trial that also involved patients at the National Institutes of Health (NIH) in Maryland, the University of California at Los Angeles, and Great Ormond Street Hospital for Children in London. The trial, funded by the NIH and the California Institute for Regenerative Medicine,… Read More »

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Should Macitentan Plus Riociguat Be Used as First-Line Therapy in PAH?

February 07, 2019 Share this content: Improvements in 6-minute walking distance scores and WHO functional class categories were seen in patients with PAH treated with macitentan plus riociguat. Upfront combination therapy with macitentan plus riociguat has demonstrated effectiveness in patients with pulmonary arterial hypertension (PAH), according to the results of a small retrospective, open-label cohort… Read More »

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